牛牛游戏厅安卓,{原始关键词}

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                            1. 当前位置: 代写一篇论文多少钱 > 医学论文 > 母婴血型不合致新生儿溶血病诊断分析

                              母婴血型不合致新生儿溶血病诊断分析

                              时间:2020-02-03 21:43作者:李丽群
                              本文导读:这是一篇关于母婴血型不合致新生儿溶血病诊断分析的文章,临床开展母婴ABO血型不合新生儿HDN疾病检测期间,需要对血清三项试验涉及的内容加强研究,之后参考新生儿娩出后的情况,及早采集血样进行试验检测,促使疾病疑似患儿能够尽快确诊治疗,早日康复出院.

                                摘要:目的 关于母婴ABO血型不合导致的新生儿溶血病(HDN)临床检测探究。方法 选择120例在我院娩出且检出疑似新生儿HDN的患儿进行研究,采集患儿血液标本,利用血清检测试验进行相关指标检测,明确属ABO溶血后,准确记录分析在新生儿出生后不同时间采血检测出的直接抗人球蛋白试验、游离抗体试验、抗体释放试验结果。结果 全部患儿经过检查,确诊新生儿HDN的例数为103例(85. 83%),出生48h内检出率最高,随着出生时间的延长,检出率逐渐下降,大部分患儿试验结果呈阳性,其中经抗体释放试验检测后阳性率高,部分检测数据比较后有差异,有统计学意义P <0. 05.结论 ABO溶血新生儿HDN临床检测时,选择在出生2天内进行疾病阳性率检测效果好,其中基于血液血清的抗体释放试验检测阳性结果为患儿疾病确诊的关键标准,如果单一进行了直接抗人球蛋白试验或者游离抗体试验,临床医生要依据检测结果与患儿发病的临床表现来确诊疾病,以期给予患儿及时且有效的治疗,减轻疾病带给患儿的诸多痛苦。

                                关键词:牛牛游戏厅安卓,{原始关键词}母婴; ABO; 血型; 不合; 新生儿; HDN; 检测;

                                作者简介:  李丽群(1988-),女,本科,初级技师,主要从事输血方向临床研究工作。E-mail:.;

                                XINSHENGERRONGXUEBING(HDN)WEIXINSHENGERSHIQIDETEYOUJIBING,SHUYURONGXUEXINGJIBING,FABINGYUANYINSHIMUYINGXUEXINGBUHE,ZHIHOUMUTIDUIYINGXUEXINGKANGTIJINGGUOTAIPANCHUANSHUJITAIER,HUIFASHENGHONGXIBAOBEIYANZHONGPOHUAIDEQINGKUANG,DAOZHIXINSHENGERHUANYOURONGXUEBING,QIZHONGABOXUEXINGBUHEFASHENGLVGAO;LINCHUANGZHENGZHUANGZHUYAOWEIHUANGDAN、SHOUZUBUXUDONG、PINXUE、SHUIZHONG、FUSHUIDENG,BUFENHUANERRUOBINGQINGYANZHONG,YICHUXIANZHILIYUYUNDONGZHANGAI,YANZHONGDEQINGKUANGXIAHUIZHISHIXINSHENGERSIWANG,GAIJIBINGDELINCHUANGZHIYUNANDUJIAODA,YUHOUXIAOGUOBUJIA,SUOYIXUYAOYUNCHANFUYUQIPEIOUZAIYUNQIJISHIJINXINGXUEXINGXITONG(ABOYURhDENG)JIANCHA,YUFANGGAIJIBING,RUGUOXINSHENGERYIJINGJIANCHURONGXUEBING,ZEXUYAOJIJIPEIHEYISHENGJINXINGTUIHUANG、BINGFAZHENGYUFANGDEZHILIAO,YIQIQUDELIXIANGDEYUHOUJIEGUO[1].YANJIUXIANJIEDUANXINSHENGERHDNDELINCHUANGJIANCHAQINGKUANG,FAXIANXUEQINGXUEJIANCHAXIAOGUO,TONGGUODUOXIANGSHIYANJIANCEYANGXINGFANYING,KETISHIXINSHENGERSHIFOUHUANYOUHDN,YICIWEIHOUXUYISHENGZHIDINGXINGZHIYOUXIAODEZHILIAOFANGANTIGONGYIJU,YOUXIAOJIANQINGGAIJIBINGJIHUANERYUJIAZHANGDAILAIDEZHUDUOTONGKUYUYALI。JIYUCIBENYANJIUXUANQU120LIYISIMUYINGABOXUEXINGBUHEXINSHENGERHDNHUANZHE,JINXINGLESHIYANSHIXUEQINGXUEJIANCE,YIJUSANXIANGSHIYANYANGXINGJIEGUOTANJIULEJIANCEXINSHENGERHDNSHIXUEYEBIAOBENCAIYANGDEZUIJIASHIJIYUJIBINGYANGXINGQUEZHENDEZHONGYAOBIAOZHUN。

                                1、资料与方法

                                1.1 一般资料

                              牛牛游戏厅安卓,{原始关键词}   XUANQUWOYUANZAI2018NIAN1YUE-2019NIAN1YUEJIESHOUDEXINSHENGERHDNHUANER120LIZUOWEIYANJIUDUIXIANGLAIYANJIU,ZHEIXIEHUANERJUNYUWOYUANMIANCHU,CHUSHENGSHIJIANBUCHAOGUO10TIAN,JINGGUOLINCHUANGYISHENGCHUBUZHENGZHUANG(HUANGDAN)JIANCHAQUEDINGWEIMUYINGABOXUEXINGBUHEDEXINSHENGERHDNYISIHUANER,WEILEJINYIBUMINGQUEBINGQING,WOYUANDUI120LIYISIXINSHENGERHDNHUANERJINXINGLESHIYANSHIXUEQINGSHIYANJIANCE;HUANERZHONGNANDUOYUNV,RENSHUFENBIEWEI70LI、50LI。

                              ABO溶血症

                              配图 ABO溶血症

                                1.2 方法

                              牛牛游戏厅安卓,{原始关键词}   CAIJI120LIHUANERKANGNINGXUEGE2ml,MUYINGXUEXINGFENBIETONGGUOCHANFUWENBINGSHIJILU、WEIZHUNINGJIAOKAJIANCEHUODE,QIZHONGHUANERZHIJIEKANGRENQIUDANBAISHIYANYETONGGUODAIANNAXINSHENGERHDNWEIZHUNINGJIAOKAJIANCEDECHU,YOULISHIYAN、KANGTISHIFANGSHIYANTONGGUOSUANFANGSANSHIJIDECHUJIANCEJIEGUO。ZHUNBEIABOGEXINGXUEYEBIAOZHUNHONGXIBAO、KANGAHUOBBIAOZHUNXUEQING、KANGRENQIUDANBAIKA(DAIANNAGONGSISHENGCHAN,DGGel CoombsKA)、LIXINJI、SUANFANGSANSHIJI(BAOKUOFANGSANYEA、FANGSANYEBHEZHONGHEYE)、SHENGLIYANSHUI、FUYUXIANG(HENGWEN37℃)DENG。(1)ZHIJIEKANGRENQIUDANBAISHIYAN:TONGGUODAIANNAXINSHENGERHDNWEIZHUNINGJIAOKASHANGJIJIANCEKEDECHU。(2)YOULIKANGTISHIYAN:QUABOGEXINGXUEYEBIAOZHUNHONGXIBAOGE50μlYICIJIARUKANGRENQIUDANBAIKAPIAN,JIANGHUANERXUEYEBIAOBENLIXIN,QUSHANGQINGYE,FENBIEQU50μlJIARUFANGYOUABOGEXINGXUEYEBIAOZHUNHONGXIBAODEKAPIANZHONG,FANGZHIFUYUXIANGFUYU15min,LIXIN,GUANCHAJIEGUO。(3)KANGTISHIFANGSHIYAN:JIANGHUANERXUEYEBIAOBENYONGSHENGLIYANSHUIXIDI,CISHUWEI3CI,QU500μlHONGXIBAOYAJIYUSHIGUANZHONG,TONGSHIJIARU500μlFANGSANHUNHEYE(A400μl+B100μl),HUNYUN,BINGLIXIN,QULIXINHOUDESHANGQINGYE400μl、FANGRUSHIGUANZHONG,YUSHIGUANZHONGJIARUZHONGHEYE3DI,ZAICILIXINHOUQUSHANGQINGYEDAIYONG,QUABOGEXINGXUEYEBIAOZHUNHONGXIBAOGE50μl,YICIJIARUKANGRENQIUDANBAIKAPIAN,YICIJIARUZAICILIXINHOUDESHANGQINGYE50μl,FANGFUYUXIANGFUYU15FENZHONG,LIXIN,GUANCHAJIEGUO。

                                1.3 观察指标

                                (1)SHIYANDEYANGXINGPANDUANBIAOZHUN,YANGXING:HONGXIBAOCHUXIANNINGJUQIEWEIYUNINGJIAOZHUDEZHONGSHANGCENG,YUXIANGYINGDEKANGTIFASHENGNINGJI;YINXING:HONGXIBAOCHUXIANNINGJUQIEWEIYUZHUDEDICENG,WEIYUXIANGYINGDEKANGTIFASHENGNINGJI。(2)YU(3)SHIYANJIANCEYANGXINGBIAOZHUNWEIJIANCHULENENGGOUYUHUANERHONGXIBAOFASHENGFANYINGDEKANGTI。HUANERXUEYEXUEQINGJINGGUOSHIYANSHIRONGXUESANXIANGSHIYANJIANCEHOU,JUNXIANSHIWEIYANGXING,TISHIHUANERHUANYOUHDN(YANGXING),DANYIJINXINGKANGTISHIFANGSHIYAN,JIEGUOCHENGYANGXINGPANDUANHUANERHDNYANGXING,QITALIANGXIANGSHIYANDANYIJIANCEYANGXINGTISHIHUANERYISIHDNYANGXING,ZHEILIANGXIANGSHIYANJIANCEYANGXINGJIEGUOFENBIELIANHE(3)SHIYANJIANCHUYANGXINGJIEGUOYULINCHUANGZHENGZHUANGHOUKEPANDUANHUANERJIBINGYANGXING。

                                1.4 统计学方法

                                SHIYONGSPSS.15RUANJIANTONGJIXUEFENXISHUJU,JISHUZILIAO[n(%)]BIAOSHI、χ2JIANYAN,P≤0.05WEISHUJUCHAYIYOUTONGJIXUEYIYI。

                                2、结果

                                CAIYANGSHIJI:120LIYISIXINSHENGERHDNDEHUANERJIANCHAHOU,KEZHI103LIYISIHUANERZUIZHONGQUEZHEN,JIANCHULVWEI85.83%,HUANERXUEYEBIAOBENCAIJISHIJIANSHEJIWEI2GESHIJIANDUAN,JIGANGCHUSHENGZHICHUSHENG2 d、3~6 d,GEGESHIJIANDUANBIAOBENCAIJILISHUGEWEI60LI,TONGGUOXUEQINGSANXIANGSHIYANYANGXINGJIANCEHOU,ZHEI2GESHIJIANDUANJIANCHUXINSHENGERHDNHUANERLISHUHEJI103LI,FENBIEWEI97LI(94.17%)、6LI(5.83%),JIANCHUHUANERLISHUJINXINGBUTONGSHIJIANDUANDESHUJUBIJIAOHOUP<0.05,YOUTONGJIXUEYIYI,QIZHONGXINSHENGERCHUSHENG2TIANNEICAIJIYANGBENJIANCHUJIBINGLVGAO,6 dZUOYOUSHIJIANCHUJIBINGRENSHUSHAO,SHUOMINGXINSHENGERHDNJIANCHULVYUYISIHUANERCHUSHENGHOUXUEYEBIAOBENCAIJISHIJIANCHENGZHENGXIANGGUANGUANXI,BIAOBENCAIJISHIJIANYUZAO,XUEQINGSANXIANGSHIYANJIANCEHOUDEYANGXINGLVYUGAO;XUEQINGJIANCEJIEGUO:103LIABOXUEXINGBUHEXINSHENGERHDNHUANERKEFENWEIMUO、O、A、B、BYUYINGA、B、AB、AB、ADEQINGKUANG,HUANERLISHUFENBIEYOU75LI、25LI、1LI、1LI、1LI,(1)、(2)、(3)XIANGSHIYANDANYIJIANCHUYANGXINGHUANERLISHUFENBIEWEI37LI(35.92%)、62LI(60.19%)、101LI(98.06%),QIZHONGZAI(1)SHIYANZHONGJINJIANCHUMUYINGO-A、O-BXUEXINGBUHEDEXINSHENGERHDNBINGLI,(2)SHIYANZHONGWEIJIANCHUB-AXUEXINGBUHEJIBINGHUANER,(3)SHIYANZHONG5LEIABOXUEXINGBUHEJIBINGHUANERJUNJIANCHU,YISHANGJIANCHUHUANERLISHUBIJIAOHOUCUNZAITONGJIXUEYIYIDECHAYIP<0.05;XUEQINGYANGXINGJIANCEJIEGUO(SHUJUJIANBIAOYI):CHUSHENGHOU~2 dCAIJIXUEYANGJIANCEXINSHENGERHDNJIBINGDEYANGXINGLVGAO,SUIZHESHIJIANDEZENGJIA,YANGXINGLVXIAJIANG,ZONGTILAIKAN(2)+(3)SHIYANJIANCEYANGXINGLVGAOYUQITASHIYANXIANGDANYIJIANCEHUOZUHEFANGSHIJIANCHULV,RUGUOTIAOJIANYUNXUJINLIANGXUANZESANXIANGHUOLIANGXIANGSHIYANLIANHEFANGSHIJIANCEYANGXINGLV,QIZHONG(3)WEIPANDUANHUANERHUANBINGDEZHUYAOYIJU,WEIZHONGDIANCESHIXIANGMU。

                              表1 患儿新生儿HDN疾病检测阳性率分析

                              患儿新生儿HDN疾病检测阳性率分析

                                3、讨论

                              牛牛游戏厅安卓,{原始关键词}   MUYINGABOXUEXINGBUHEDEXINSHENGERHDNJIBINGDECHANGJIANLEIXINGWEIABOXUEXINGXITONG,YIBANZAIXINSHENGERZAOQIHUOZHEZAITAIERJIEDUANFASHENG,HUANBINGHUANERDADUOSHUQINGKUANGXIAYUSHENTIJIANKANGDEXINSHENGERMEIYOUSHENMEQUBIE,DANSHIMIANCHUHOU~48 hZUOYOUSHI,HUICHUXIANHUANGDANZHENGZHUANG,ZHIHOUSUIZHEXINSHENGERRILINGDEZENGJIA,JITIPIFUHUANGRANQINGKUANGHUIYUJIAYANZHONG,CISHIHUANERHUICHUXIANPINXUE、HEHUANGDANDENGZHENGZHUANG,SHENZHISIWANG,SUOYIXINSHENGERGAIJIBINGDEZAOFAXIANYUZAOZHILIAOFEICHANGZHONGYAO,BENYANJIUBIANDUIXINSHENGERHDNDELINCHUANGZHENDUANQINGKUANGJINXINGLEXIANGXITANJIU,ZHONGDIANFENXILEXUEQINGXUEJIANYANDUIYUJIBINGZHENDUANQUEZHENDEJIAZHI[2,3].XUEQINGXUESANXIANGJIANYANWEIMUQIANJIANCHAZHENDUANXINSHENGERHDNDEYOUXIAOFANGFA,TONGGUOZHIJIEKANGQIUDANBAI、YOULIKANGTI、KANGTISHIFANGSHIYANKEYIJIANGXINSHENGERDEHUANBINGQINGKUANGJIAOWEIJINGQUEDEJIANCHACHU,ERQIEJIANCEANQUANXINGGAO,ZAIXINSHENGERDEGAIZHONGMIANYIJIBINGQUEZHENZHONGKEYIDUOJINXINGYINGYONGYUTUIGUANG[4].BENYANJIUQIJIANXUANZEDE120LIYISIXINSHENGERHDNJUNJIESHOULEXUEQINGSANXIANGSHIYANJIANCE,QIZHONGZAIXUEYANGCAIJIFANGMIAN,FENWEILE2GESHIJIANJINXINGCAIYANG,JIEHEYANJIUJIEGUOFAXIANXUEYEBIAOBENCAIJISHIJIANYUSHIYANJIANCEJIEGUOCUNZAIGUANLIAN,YOUQISHIZAIXINSHENGERGANGMIANCHUSHI,BUCHAOGUO48 hJIANCE,KEYIDIYISHIJIANJIANCHUJIBING,CHAOGUOGAISHIJIANCAIXUEJIANCE,SUIRANYENENGJIANCHUXINSHENGERDEJIBING,DANSHIJIANCHULVHUIZHUJIANJIANGDI,YANZHONGYINGXIANGXINSHENGERJIBINGDEYOUXIAOZHILIAOYUKANGFU,TISHIXINSHENGERHDNJIBINGZHENDUANSHIYINGZAICHUSHENGHOUJINKUAIJINXINGXUEQINGXUEJIANCE,YIBIANYISHENGKEYIZHUAZHUJIBINGZHILIAODEZUIJIASHIJIKONGZHIJIBING;TONGSHIZAIJIANCEQIJIAN,YAOZHUYISANXIANGSHIYANJINLIANGDOUYAOJIANCE,QIZHONGKANGTISHIFANGSHIYANDEJIANCEJIEGUOJUYOUJIAOGAODEJIBINGQUEZHENCANKAOJIAZHI,XUYAOYISHENGDUIGAIYANGXINGJIEGUOJINXINGZHUNQUEFENXI,RUGUOWEIQITALIANGXIANGSHIYANDANYIJINXING,ZEXUYAOJIEHEDISANXIANGSHIYANJIEGUOJIYISIHUANERLINCHUANGBINGZHENGBIAOXIAN,ZONGHEDUOFANGZILIAOSHUJU,DECHUJIBINGDEZUIZHONGQUEZHENJIEGUO,YANJIUQIJIANDEBUFENSHUJUJINXINGBIJIAOHOU,CUNZAIZHEJIAODACHAYIYUTONGJIXUEYIYIP<0.05.

                                ZONGSHANGSUOSHU,LINCHUANGKAIZHANMUYINGABOXUEXINGBUHEXINSHENGERHDNJIBINGJIANCEQIJIAN,XUYAODUIXUEQINGSANXIANGSHIYANSHEJIDENEIRONGJIAQIANGYANJIU,ZHIHOUCANKAOXINSHENGERMIANCHUHOUDEQINGKUANG,JIZAOCAIJIXUEYANGJINXINGSHIYANJIANCE,CUSHIJIBINGYISIHUANERNENGGOUJINKUAIQUEZHENZHILIAO,ZAORIKANGFUCHUYUAN[5,6].

                                CANKAOWENXIAN

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                                [4] 刘文东,赵珺,矫岩,张春菊。不同ABO及Rh血型孕妇相关抗体效价检测及对新生儿溶血病的关系[J].中国生育健康杂志,2018,29(06):565-566+575.
                                [5] 王洁。南昌市O型血孕妇Ig G抗体效价与新生儿ABO溶血病的相关性[J].实验与检验医学,2018,36(05):790-792.
                                [6] 田春梅。新生儿溶血病ABO血型免疫性抗体检测分析[J].中西医结合心血管病电子杂志,2018,6(27):13+16.

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